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645 S PRINCE STREETLANCASTER, PA 17603




Prime Mixed-Use Opportunity in Lancaster City. Unlock the full potential of this fully renovated mixed-use property, prominently positioned on a high-visibility corner at a signalized intersection with an average daily traffic count of 11,849 vehicles—delivering unbeatable exposure for your business. This turnkey building offers the ideal combination of commercial and residential space, perfect for maximizing cash flow and long-term investment returns. The first-floor commercial unit has been thoughtfully laid out with five partitioned rooms, two restrooms, a welcoming reception area, and a stylish coffee bar. Designed for flexibility, this space is perfectly suited for a professional office, salon, nail studio, boutique retail, or barber shop. Thanks to clear-span ceiling joists, the interior walls can be easily removed to accommodate open layouts for other uses, including a convenience store or studio space. With modern finishes, fresh interiors, and large storefront windows, this space is move-in ready for your business. Above, a bright and spacious two-bedroom apartment features a private entrance and updated finishes throughout, making it ideal for a short-term Airbnb rental or long-term tenant. The layout, natural light, and contemporary upgrades make it equally appealing to renters and owner-occupants seeking to live in the heart of Lancaster City. The entire building has been renovated from top to bottom, including a new roof, HVAC system, plumbing, electrical, flooring, and paint. Two off-street parking spots and ample street parking nearby offer rare convenience in the city. With excellent curb appeal and a location just minutes from downtown Lancaster’s vibrant shops, cafés, restaurants, and cultural destinations, this property stands out as a smart and forward-thinking investment. Whether you’re an entrepreneur seeking a live/work opportunity or an investor looking to diversify with multiple income streams, 645 S Prince Street offers flexibility, visibility, and value in one of Lancaster’s fastest-growing corridors. Schedule your private tour today and see the potential for yourself.
4 days ago | Status changed to Pending | |
4 days ago | Listing updated with changes from the MLS® | |
a month ago | Listing first seen on site |

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